The Cure to Skin Cancer: A Metabolic Approach
Department
Biological Sciences
Major
Biological Sciences
Research Advisor
Westenberg, David J.
Advisor's Department
Biological Sciences
Abstract
Mycosporines are naturally synthesized metabolites found in bacteria that are constantly exposed to sunlight. The mycosporines help to absorb UV radiation and therefore, keep the UV radiation from disrupting the DNA of the cell. Although our skin is host to many different bacteria, none of them produce mycosporines. There are three genes responsible for producing the mycosporine in the cyanobacterium, Nostoc punctiforme. Using a plasmid as a vector, these genes will be transferred to Staphylococcus epidermidis, a natural inhabitant of human skin. The S. epidermidis will then be able to produce their own mycosporine. Applying the S. epidermidis to our skin via a lotion, we will be protected from harmful UV radiation. Horizontal gene transfer on our skin could lead to more bacteria producing the mycosporines and thus, a greater UV protection.
Biography
Peter is a junior at Missouri S&T. His fascination with microbiology lies in the application of microbes in our daily life. He is a captain of the men’s varsity soccer team here at school and spends much of his time playing the sport. Peter maintains a high GPA while also being involved in extracurriculars.
Research Category
Sciences
Presentation Type
Poster Presentation
Document Type
Poster
Location
Upper Atrium/Hallway
Presentation Date
10 Apr 2012, 9:00 am - 11:45 am
The Cure to Skin Cancer: A Metabolic Approach
Upper Atrium/Hallway
Mycosporines are naturally synthesized metabolites found in bacteria that are constantly exposed to sunlight. The mycosporines help to absorb UV radiation and therefore, keep the UV radiation from disrupting the DNA of the cell. Although our skin is host to many different bacteria, none of them produce mycosporines. There are three genes responsible for producing the mycosporine in the cyanobacterium, Nostoc punctiforme. Using a plasmid as a vector, these genes will be transferred to Staphylococcus epidermidis, a natural inhabitant of human skin. The S. epidermidis will then be able to produce their own mycosporine. Applying the S. epidermidis to our skin via a lotion, we will be protected from harmful UV radiation. Horizontal gene transfer on our skin could lead to more bacteria producing the mycosporines and thus, a greater UV protection.
