Bioactive Glass Composites for Bone and Musculoskeletal Tissue Engineering
Abstract
Bioactive glass composites, composed of a bioactive glass phase and another solid phase, typically a biodegradable polymer, can provide significant property and manufacturing advantages over the individual biomaterials for use in bone and musculoskeletal tissue engineering. While bioactive glasses have been studied and applied for more than five decades, bioactive glass composites have received far less attention. Advances in the last 10–15 years are generating heightened interest in the use of bioactive glass composites, particularly in bone tissue engineering. Successful applications of bioactive glass composites will benefit from the attractive properties of bioactive glasses (bioactivity, mechanical strength, stimulation of gene expression) while avoiding the disadvantages (brittleness; difficulties of forming into anatomically relevant shapes). This chapter will describe the materials science of bioactive glass composites, the in vitro and in vivo performance of these composites, and emerging developments in their use in bone and musculoskeletal tissue engineering.
Recommended Citation
M. N. Rahaman et al., "Bioactive Glass Composites for Bone and Musculoskeletal Tissue Engineering," Bioactive Glasses: Materials, Properties and Applications, Second Edition, pp. 285 - 336, Elsevier, Jan 2017.
The definitive version is available at https://doi.org/10.1016/B978-0-08-100936-9.00013-7
Department(s)
Materials Science and Engineering
Keywords and Phrases
Bioactive glass composites; Bone tissue engineering; Creation of bioactive glass composites; In vitro properties of bioactive glass composites; In vivo performance of bioactive glass composites; Musculoskeletal tissue engineering
International Standard Book Number (ISBN)
978-008100936-9;978-008100937-6
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2024 Elsevier, All rights reserved.
Publication Date
01 Jan 2017
