Abstract
A method for preparing nonradioactive microspheres adapted for radiation synovectomy of arthritic joints in a mammal involves forming the microspheres by doping a biodegradable glass material which may be lithium or potassium silicate, lithium or potassium aluminosilicate, lithium or potassium aluminoborate, lithium or potassium germanate or lithium or potassium alumino- germanate with an isotope which may be samarium, holmium, erbium, dysprosium, rhemium or yttrium so that the isotope is chemcially dissolved in and distributed uniformly throughout the glass material. The doped glass material is then treated with an acid wash to produce a thin layer on the surface thereof and heat treated to improve the chemical durability of the glass material by rendering the solubility of the layer lower than that of the underlying glass material.
Recommended Citation
D. E. Day and G. J. Ehrhardt, "Composition and Method for Radiation Synovectomy of Arthritic Joints," U.S. Patents, Aug 1991.
Department(s)
Materials Science and Engineering
Patent Application Number
US07/408,087
Patent Number
US5039326A
Document Type
Patent
Document Version
Final Version
File Type
text
Language(s)
English
Rights
© 1991 The Curators of the University of Missouri, All rights reserved.
Publication Date
13 Aug 1991
