Abstract
Radioactive microspheres for radiation synovectomy of arthritic joints in a mammal comprises a biodegradable glass material and a beta radiation emitting radioisotope chemically dissolved in and distributed substantially uniformly throughout the glass material. The biodegradable glass material may be lithium silicate, lithium aluminosilicate, lithium aluminoborate, lithium germa- nate, lithium aluminogermanate, potassium silicate, potassium aluminosilicate, potassium aluminoborate, potassium germanate or potassium aluminogermanate and the beta radiation emitting radioisotope may be samarium-153, holmium-166, erbium-169, dysprosium-165, rhenium-186, rhenium-188 or yttrium-90. Method for preparing such microspheres and for carrying out radiation synovectomy of arthritic joints utilizing such microspheres are also disclosed.
Recommended Citation
D. E. Day and G. J. Ehrhardt, "Composition and Method for Radiation Synovectomy of Arthritic Joints," U.S. Patents, Apr 1991.
Department(s)
Materials Science and Engineering
Patent Application Number
US07/408,115
Patent Number
US5011797A
Document Type
Patent
Document Version
Final Version
File Type
text
Language(s)
English
Rights
© 1991 The Curators of the University of Missouri, All rights reserved.
Publication Date
30 Apr 1991