Abstract

Radioactive microspheres for radiation synovectomy of arithmetic joints in a mammal comprise a biodegradable glass material and a beta radiation emitting radioisotope chemically dissolved in and distributed substantially uniformly throughout the glass material. The biodegradable glass material may be lithium silicate, lithium aluminosilicate, lithium aluminoborate, lithium germa- nate, lithium aluminogermanate, potassium silicate, potassium aluminosilicate, potassium, aluminoborate, potassium germanate or potassium aluminogermanate and the beta radiation emitting radioisotope may be samarium-153, holmium-166, erbium-169, dysprosium-165, rhenium-186, rhenium-188 or yttrium-90. Methods for preparing such microspheres and for carrying out radiation synovectomy of arthritic joints utilizing such microspheres are also disclosed.

Department(s)

Materials Science and Engineering

Patent Application Number

US07/150,154

Patent Number

US4889707A

Document Type

Patent

Document Version

Final Version

File Type

text

Language(s)

English

Rights

© 1989 The Curators of the University of Missouri, All rights reserved.

Publication Date

26 Dec 1989

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