Abstract
An exposure that is reproducible across clinical/laboratory environments, and appealing to subjects, is described here. Digital music files are level-equated within and across songs such that playlists deliver an exposure that is consistent across time. Modified music is more pleasant to listen to than pure tones or shaped noise and closely follows music exposures subjects may normally experience. Multiple therapeutics reduce noise-induced hearing loss in animals, but human trial design is complicated by limited access to noise-exposed subject populations. The development of standard music exposure parameters for temporary threshold shift studies would allow comparison of protection across agents with real-world relevant stimuli in human subjects. © 2011 Acoustical Society of America.
Recommended Citation
C. G. Le Prell et al., "Modification Of Digital Music Files For Use In Human Temporary Threshold Shift Studies," Journal of the Acoustical Society of America, vol. 130, no. 4, pp. EL142 - EL146, Acoustical Society of America, Oct 2011.
The definitive version is available at https://doi.org/10.1121/1.3630017
Department(s)
Electrical and Computer Engineering
Publication Status
Open Access
International Standard Serial Number (ISSN)
0001-4966
Document Type
Article - Journal
Document Version
Final Version
File Type
text
Language(s)
English
Rights
© 2025 Acoustical Society of America, All rights reserved.
Publication Date
01 Oct 2011
PubMed ID
21974483
Comments
National Institutes of Health, Grant U01DC008423