Abstract
An enzymatic, fluorescent glucose sensor was constructed with a novel epoxy-Based, optically transparent dry film resist (PerMX 3000 series, DuPont). This material was utilized as the main active material for fluidic structure and optical interrogation. This sensor was based on the enzymatic reaction of glucose oxidase (GOD) and utilized a ruthenium complex fluorophore as the reporting agent. Both the oxygen-sensitive ruthenium complex and GOD were incorporated into poly (ethylene glycol) (PEG)-Based hydrogel materials, which were lithographically patterned and embedded inside the PerMX fluidic channel after wafer-bonding process. the optofluidic sensing platform with this embedded sensing elements exhibited a wide dynamic range of 0-20 mM (0-360 mg/dl) glucose with good sensitivity. This finding demonstrates the promise of PerMX-Based fluidic systems as platforms for various optofluidic assays. © 2011 IEEE.
Recommended Citation
Z. Gao et al., "Optofluidic Glucose Sensor Utilizing an Epoxy-Based, Transparent Dry Film Resist," Proceedings of IEEE Sensors, pp. 284 - 287, article no. 6127035, Institute of Electrical and Electronics Engineers, Dec 2011.
The definitive version is available at https://doi.org/10.1109/ICSENS.2011.6127035
Department(s)
Electrical and Computer Engineering
Second Department
Chemical and Biochemical Engineering
International Standard Book Number (ISBN)
978-142449288-6
Document Type
Article - Conference proceedings
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2024 Institute of Electrical and Electronics Engineers, All rights reserved.
Publication Date
01 Dec 2011
Included in
Biochemical and Biomolecular Engineering Commons, Electrical and Computer Engineering Commons
