Structure and properties of Y₂O₃-Al₂O₃-SiO₂ glasses

Author

Erik M. Erbe

Abstract

"This dissertation is the culmination of the investigation of several aspects of the Y₂O₃-Al₂O₃-SiO₂ (YAS) glass forming system. This glass system is of particular interest for use as a neutron-activatable glass capable of being used as a radiopharmaceutical. There has been some promising research using YAS glass microspheres for the localized treatment of liver cancer. The objective of this research is to further define and characterize the relevant glass properties in this system for use in the treatment of liver cancer and other radiation therapies.

The Y₂O₃-Al₂O₃-SiO₂ system has been characterized previously by basic glass property evaluation. This dissertation investigates some of the specific properties related to the application and others of purely scientific interest more completely and in depth. The main body of this work will be presented in five papers that will be submitted for publication; the first on conventionally melted and sol-gel derived Y₂O₃-Al₂O₃-SiO₂ glasses, the second on the formation of Y₂O₃-Al₂O₃-SiO₂ glass microspheres by sol-gel, the third on the chemical durability of the Y₂O₃-Al₂O₃-SiO₂ glasses for use in-vivo, and the fourth and fifth, a structural study of Y₂O₃-Al₂O₃-SiO₂glasses made by conventional melting and sol-gel methods.

The first three papers cover the aspects of the Y₂O₃-Al₂O₃-SiO₂ glass formation and characterization for use in radiopharmaceutical applications. The latter papers examine the structure of the Y₂O₃-Al₂O₃-SiO₂ glasses and is of purely scientific interest"--Abstract, page iii.

Advisor(s)

Day, D. E.

Committee Member(s)

Moore, Robert E., 1930-2003
Rahaman, M. N., 1950-
Blum, Frank D.
Podzimek, Josef, 1923-2007
Ehrhardt, Gary

Department(s)

Materials Science and Engineering

Degree Name

Ph. D. in Ceramic Engineering

Publisher

University of Missouri--Rolla

Publication Date

Spring 1991

Journal article titles appearing in thesis/dissertation

• Conventionally Melted and Sol-Gel Derived Y₂O₃-Al₂O₃-SiO₂ Glasses
• Formation of Sol-Gel Derived Y₂O₃-Al₂O₃-SiO₂ Glass Microspheres
• Chemical Durability of Y₂O₃-Al₂O₃-SiO₂ Glasses for the in-vivo Delivery of β Radiation
• Structural Study of Conventionally Melted and Sol-Gel Derived Y₂O₃-Al₂O₃-SiO₂ Glasses: I, ²⁷Al & ²⁹Si MAS NMR Spectra
• Structural Study of Conventionally Melted and Sol-Gel Derived Y₂O₃-Al₂O₃-SiO₂ Glasses: II, Raman and Infrared Spectra

Pagination

xx, 195 pages

Note about bibliography

Includes bibliographical references.

Rights

© 1991 Erik Michael Erbe, All rights reserved.

Document Type

Dissertation - Restricted Access

File Type

text

Language

English

Thesis Number

T 6399

Print OCLC #

28296864

Recommended Citation

Erbe, Erik M., "Structure and properties of Y₂O₃-Al₂O₃-SiO₂ glasses" (1991). Doctoral Dissertations. 993.
https://scholarsmine.mst.edu/doctoral_dissertations/993