Bubble Fractionation of Enantiomers from Solution using Molecularly Imprinted Polymers as Collectors

Author

Daniel W. Armstrong, Missouri University of Science and Technology
J. M. Schneiderheinze
Y. S. Hwang
B. Sellergren

Abstract

Adsorptive bubble separation methods have been used to enrich components from both heterogeneous and homogeneous solutions. These methods are particularly effective for processing large solution volumes at low cost Previous work demonstrated that chiral, surface-active collectors could be used to enrich enantiomers from homogeneous solution in a foam fractionation process. In a significant extension of this work, the use of highly selective molecularly imprinted polymers (MIPs) and heterogeneous solutions for the bubble flotation of enantiomers was evaluated. The high selectivity and ease of recycling of the MIP make this a potentially powerful approach for process-scale separations from large-volume bulk solutions. New MIPs were produced with low swelling properties which allowed them to retain enantioselectivity after numerous recyclings.

Recommended Citation

D. W. Armstrong et al., "Bubble Fractionation of Enantiomers from Solution using Molecularly Imprinted Polymers as Collectors," Analytical Chemistry, vol. 70, no. 17, pp. 3717 - 3719, American Chemical Society, Sep 1998.

The definitive version is available at https://doi.org/10.1021/ac980154l

Department(s)

Chemistry

Comments

National Institute of General Medical Sciences, Grant R01GM053825

International Standard Serial Number (ISSN)

0003-2700

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2024 American Chemical Society, All rights reserved.

Publication Date

01 Sep 1998

PubMed ID

9737214