Separation Of Homologous And Isomeric Alkaloids Related To Nicotine On A Β-cyclodextrin-bonded Phase
Abstract
Nicotine and thirteen structurally related alkaloids were separated with a β-cyclodextrin-bonded phase column. The retention of homologous compounds tends to increase as the size of the homolog increases. Structural isomers in which the pyridine nitrogen is in the 4-position are always retained the longest. Both retention and efficiency are very pH dependent. Conversely, selectivity does not change significantly with pH. © 1989.
Recommended Citation
J. I. Seeman et al., "Separation Of Homologous And Isomeric Alkaloids Related To Nicotine On A Β-cyclodextrin-bonded Phase," Journal of Chromatography A, vol. 483, pp. 169 - 177, Elsevier, Jan 1989.
The definitive version is available at https://doi.org/10.1016/S0021-9673(01)93119-X
Department(s)
Chemistry
International Standard Serial Number (ISSN)
0021-9673
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2023 Elsevier, All rights reserved.
Publication Date
01 Jan 1989
