Abstract
A quantitative method is developed and presented for estimating the mean pore diameter, d(pore), that could allow intraparticle fluid flow in the macroporous region of adsorbent particles with a bidisperse porous structure packed in a column. The method is used to estimate the value of d(pore) that is required to obtain specified values of the fraction, F, of the column superficial fluid velocity that is flowing through the macroporous region of the adsorbent particles and the value of d(pore) that is required to obtain specified values of the intraparticle Peclet number, Pe(intra).
Recommended Citation
G. A. Heeter and A. I. Liapis, "Estimation of Pore Diameter for Intraparticle Fluid Flow in Hidisperse Porous Chromatographic Particles," Journal of Chromatography A, vol. 761, no. 1 thru 2, pp. 35 - 40, Elsevier, Feb 1997.
The definitive version is available at https://doi.org/10.1016/S0021-9673(96)00791-1
Department(s)
Chemical and Biochemical Engineering
Keywords and Phrases
Adsorbents; Intraparticle fluid flow; Mathematical models; Perfusion chromatography; Pore size; Porous adsorbent particles; Proteins
International Standard Serial Number (ISSN)
0021-9673
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2024 Elsevier, All rights reserved.
Publication Date
14 Feb 1997
