Abstract
C-peptide is produced, processed, and secreted with insulin, and appears to exert separate but intimately related effects. In this review, we address the existence of the C-peptide receptor, the interaction between C-peptide and insulin, and the potential physiological significance of proinsulin C-peptide. C-peptide is produced, processed, and secreted with insulin, and appears to exert separate but intimately related effects. In this review, we address the existence of the C-peptide receptor, the interaction between C-peptide and insulin, and the potential physiological significance of proinsulin C-peptide.
Recommended Citation
G. L. Yosten and G. R. Kolar, "The Physiology of Proinsulin C-peptide: Unanswered Questions and a Proposed Model," Physiology, vol. 30, no. 4, pp. 327 - 332, American Physiological Society, Jul 2015.
The definitive version is available at https://doi.org/10.1152/physiol.00008.2015
Department(s)
Biological Sciences
International Standard Serial Number (ISSN)
1548-9221; 1548-9213
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2025 American Physiological Society, All rights reserved.
Publication Date
01 Jul 2015
PubMed ID
26136546
