Department
Chemical and Biochemical Engineering
Major
Chemical Engineering
Research Advisor
Wang, Jee-Ching
Advisor's Department
Chemical and Biochemical Engineering
Funding Source
OURE Scholarship; Missouri University Science and Technology Chemical Engineering Department
Abstract
Lipopolysaccharides (LPS), also known as endotoxins, are toxins released from the cell walls of gram-negative bacteria upon their death. Ingestion of LPS by humans or animals can initiate inflammatory immune responses, resulting in blood vessels dilation, organ dysfunction and potential death. These toxins contaminate a variety of manufacturing processes from the pharmaceutical industry to animal feed production, posing a risk to humans and animals alike. This study details the production of PCL nanoparticle capable of removing LPS from water and a preliminary analysis of the removal efficiency. The outcomes of this research hold significant implications for industries reliant on bacterial cultures and biological material, offering an inexpensive potential solution to mitigate LPS contamination.
Biography
Mikaela Ritchie is a senior studying Biochemical Engineering at Missouri University of Science and Technology. She enjoys combining her knowledge of math, physics, chemistry and biology in research beneficial across industries. Outside of the lab, Mikaela enjoys serving in her local community as well as traveling to Central America with various Christian ministries and humanitarian efforts.
Research Category
Engineering
Presentation Type
Poster Presentation
Document Type
Poster
Location
Innovation Forum - 1st Floor Innovation Lab
Presentation Date
10 April 2024, 1:00 pm - 4:00 pm
The Application of Poly-ε-caprolactone Nanoparticles for Endotoxin Removal
Innovation Forum - 1st Floor Innovation Lab
Lipopolysaccharides (LPS), also known as endotoxins, are toxins released from the cell walls of gram-negative bacteria upon their death. Ingestion of LPS by humans or animals can initiate inflammatory immune responses, resulting in blood vessels dilation, organ dysfunction and potential death. These toxins contaminate a variety of manufacturing processes from the pharmaceutical industry to animal feed production, posing a risk to humans and animals alike. This study details the production of PCL nanoparticle capable of removing LPS from water and a preliminary analysis of the removal efficiency. The outcomes of this research hold significant implications for industries reliant on bacterial cultures and biological material, offering an inexpensive potential solution to mitigate LPS contamination.
