What is the function of the Iqg1 domain during Cytokinesis?
Department
Biological Sciences
Major
Biological Sciences
Research Advisor
Shannon, Katie
Advisor's Department
Biological Sciences
Funding Source
OURE
Abstract
In this experiment, we are specifically looking at the final step in cell division which is cytokinesis. Cytokinesis is the final stage of cell division during which the two daughter cells separate completely. For this experiment, budding yeast is used to see multiple cell divisions in a short period of time due to the microbe being such a good model organism. After breaking down the budding yeast, the IQG1 protein has held an essential interest in the involvement of the actin-myosin ring assembly. The goal of this research was to enter a plasmid within the yeast genome of the IQG1-wt with deletion, making the mitosis of the division abnormal. Once the cells are abnormal, the cells are then starved to force sporulation, enabling tetrads within the cells to go through meiosis as spores until probable conditions arise. With more research on IQG1 and the role it plays in cell division, the more researchers can understand the effects of the gene protein and the functions that arrive when abnormal.
Biography
Lauren Tolan is a 20 year old Missouri S&T student who is studying to become an orthopedic surgeon with an emphasis in sports medicine. She is involved in numerous clubs and activities here on campus including Miner Club, Women’s Soccer, Scrubs, and Phi Sigma Honors Society; just to name a few. When she has free time, she likes to spend time with her friends and family, sewing to a marvels or Disney movie, working as a student athletic trainer, and numerous other activities. Lauren is a passionate worker and an enthusiastic soul with a thirst for medicine. Seeing every aspect of medicine really makes her heart soar!
Research Category
Social Sciences
Presentation Type
Poster Presentation
Document Type
Poster
Location
Upper Atrium
Presentation Date
17 Apr 2018, 9:00 am - 12:00 pm
What is the function of the Iqg1 domain during Cytokinesis?
Upper Atrium
In this experiment, we are specifically looking at the final step in cell division which is cytokinesis. Cytokinesis is the final stage of cell division during which the two daughter cells separate completely. For this experiment, budding yeast is used to see multiple cell divisions in a short period of time due to the microbe being such a good model organism. After breaking down the budding yeast, the IQG1 protein has held an essential interest in the involvement of the actin-myosin ring assembly. The goal of this research was to enter a plasmid within the yeast genome of the IQG1-wt with deletion, making the mitosis of the division abnormal. Once the cells are abnormal, the cells are then starved to force sporulation, enabling tetrads within the cells to go through meiosis as spores until probable conditions arise. With more research on IQG1 and the role it plays in cell division, the more researchers can understand the effects of the gene protein and the functions that arrive when abnormal.
