Sleep Responses to Starvation and Sleep Deprivation in Drosophila melanogaster

Presenter Information

Sahitya Injamuri

Department

Biological Sciences

Major

Biological Sciences

Research Advisor

Thimgan, Matthew S.
Olbricht, Gayla R.

Advisor's Department

Biological Sciences

Second Advisor's Department

Mathematics and Statistics

Abstract

Sleep deprivation and starvation both produce increased waking in Drosophila during the period of treatment, but both produced a different post-treatment response. After flies undergo sleep deprivation an increase in sleep is observed compared to sleep baseline. However, in flies that experience starvation conditions sleep tends to return to the pretreatment level. We will use mathematical modeling of sleep to determine any subtle differences in sleep patterns pre and post treatment. Males and females of three different genotypes will be used. These mutant genotypes include tim 01, cyc 01, which lack a circadian rhythm. The wild type, CS Skeath, will be used as a control. These flies will be placed in complete darkness for 48 hours and then are sleep deprived by either sleep deprivation or starvation for 12 hours. Post treatment sleep is measured for 48 hours, and analysis is done to detect a difference.

Biography

Sahitya Injamuri was born in India and moved to the United States when she was four. She is a senior in Biological Sciences at Missouri University of Science and Technology. She is also the vice-president of Helix, the university’s chapter of the American Society of Microbiology and a member of Phi Sigma, Biological Honors Society. After graduation, Sahitya plans to go to graduate school in pathology.

Research Category

Sciences

Presentation Type

Poster Presentation

Document Type

Poster

Location

Upper Atrium/Hall

Presentation Date

15 Apr 2015, 9:00 am - 11:45 am

Comments

Joint project with Shelby McNeil

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Apr 15th, 9:00 AM Apr 15th, 11:45 AM

Sleep Responses to Starvation and Sleep Deprivation in Drosophila melanogaster

Upper Atrium/Hall

Sleep deprivation and starvation both produce increased waking in Drosophila during the period of treatment, but both produced a different post-treatment response. After flies undergo sleep deprivation an increase in sleep is observed compared to sleep baseline. However, in flies that experience starvation conditions sleep tends to return to the pretreatment level. We will use mathematical modeling of sleep to determine any subtle differences in sleep patterns pre and post treatment. Males and females of three different genotypes will be used. These mutant genotypes include tim 01, cyc 01, which lack a circadian rhythm. The wild type, CS Skeath, will be used as a control. These flies will be placed in complete darkness for 48 hours and then are sleep deprived by either sleep deprivation or starvation for 12 hours. Post treatment sleep is measured for 48 hours, and analysis is done to detect a difference.