Title

"Insulin Neck": Is this the Earliest Sign of Insulin Resistance?

Presenter Information

Katie Payne

Department

Biological Sciences

Major

Biological Sciences

Research Advisor

Aronstam, Robert
Stoecker, William V.

Advisor's Department

Biological Sciences

Second Advisor's Department

Chemistry

Abstract

Acanthosis nigricans (AN) is so closely linked with insulin resistance (IR) that it has been called a "clinical surrogate" for laboratory-determined hyperinsulinemia. 1 AN presence can therefore indicate patients with IR, allowing implementation of interventions that may prevent progression to type 2 diabetes mellitus (DM). 2 We report 30 patients who presented with elevated body mass index (BMI) to correlate IR with different AN physical findings. Insulin neck (visibly increased texture on the posteriolateral neck) is the most sensitive physical finding for insulin resistance (IR). Insulin neck appears as visible lines, and/or furrows and ridges on the posterolateral neck. If neck texture is normal, IR is less likely to be present.

Biography

Katie is a Junior and full-time Research Coordinator of Stoecker and Associates. She plans to matriculate in a medical school of her choice after obtaining her B. S. in Biological Sciences at Missouri S& T. She is excited to share her latest clinical observation project and is proud to announce that it will be appearing in an upcoming issue of JAMA Dermatology.

Research Category

Sciences

Presentation Type

Oral Presentation

Document Type

Presentation

Award

Sciences oral presentation, Second place

Location

Turner Room

Presentation Date

03 Apr 2013, 10:30 am - 11:00 am

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Apr 3rd, 10:30 AM Apr 3rd, 11:00 AM

"Insulin Neck": Is this the Earliest Sign of Insulin Resistance?

Turner Room

Acanthosis nigricans (AN) is so closely linked with insulin resistance (IR) that it has been called a "clinical surrogate" for laboratory-determined hyperinsulinemia. 1 AN presence can therefore indicate patients with IR, allowing implementation of interventions that may prevent progression to type 2 diabetes mellitus (DM). 2 We report 30 patients who presented with elevated body mass index (BMI) to correlate IR with different AN physical findings. Insulin neck (visibly increased texture on the posteriolateral neck) is the most sensitive physical finding for insulin resistance (IR). Insulin neck appears as visible lines, and/or furrows and ridges on the posterolateral neck. If neck texture is normal, IR is less likely to be present.