"Insulin Neck": Is this the Earliest Sign of Insulin Resistance?
Department
Biological Sciences
Major
Biological Sciences
Research Advisor
Aronstam, Robert
Stoecker, William V.
Advisor's Department
Biological Sciences
Second Advisor's Department
Chemistry
Abstract
Acanthosis nigricans (AN) is so closely linked with insulin resistance (IR) that it has been called a "clinical surrogate" for laboratory-determined hyperinsulinemia. 1 AN presence can therefore indicate patients with IR, allowing implementation of interventions that may prevent progression to type 2 diabetes mellitus (DM). 2 We report 30 patients who presented with elevated body mass index (BMI) to correlate IR with different AN physical findings. Insulin neck (visibly increased texture on the posteriolateral neck) is the most sensitive physical finding for insulin resistance (IR). Insulin neck appears as visible lines, and/or furrows and ridges on the posterolateral neck. If neck texture is normal, IR is less likely to be present.
Biography
Katie is a Junior and full-time Research Coordinator of Stoecker and Associates. She plans to matriculate in a medical school of her choice after obtaining her B. S. in Biological Sciences at Missouri S& T. She is excited to share her latest clinical observation project and is proud to announce that it will be appearing in an upcoming issue of JAMA Dermatology.
Research Category
Sciences
Presentation Type
Oral Presentation
Document Type
Presentation
Award
Sciences oral presentation, Second place
Location
Turner Room
Presentation Date
03 Apr 2013, 10:30 am - 11:00 am
"Insulin Neck": Is this the Earliest Sign of Insulin Resistance?
Turner Room
Acanthosis nigricans (AN) is so closely linked with insulin resistance (IR) that it has been called a "clinical surrogate" for laboratory-determined hyperinsulinemia. 1 AN presence can therefore indicate patients with IR, allowing implementation of interventions that may prevent progression to type 2 diabetes mellitus (DM). 2 We report 30 patients who presented with elevated body mass index (BMI) to correlate IR with different AN physical findings. Insulin neck (visibly increased texture on the posteriolateral neck) is the most sensitive physical finding for insulin resistance (IR). Insulin neck appears as visible lines, and/or furrows and ridges on the posterolateral neck. If neck texture is normal, IR is less likely to be present.
