Location
Innovation Lab Atrium
Start Date
4-2-2025 10:00 AM
End Date
4-2-2025 11:30 AM
Presentation Date
2 April 2025, 10:00am - 11:30am
Biography
Jenna Mueller is a sophomore majoring in Biological Sciences and minoring in Chemistry at Missouri S&T. Along with working in Dr. Shannon’s research lab, Jenna is a pole vaulter on the S&T Track and Field team and is the Vice President of the International Genetically Engineered Machines (iGEM) design team on campus. Jenna aspires to pursue a career in research, focusing on cell and molecular biology or microbiology. Outside of academics and athletics, she enjoys hiking, reading, and watching movies.
Meeting Name
2025 - Miners Solving for Tomorrow Research Conference
Department(s)
Biological Sciences
Second Department
Chemistry
Document Type
Poster
Document Version
Final Version
File Type
text
Language(s)
English
Rights
© 2025 The Authors, All rights reserved
Included in
Biochemistry, Biophysics, and Structural Biology Commons, Cell and Developmental Biology Commons
The Effects of Preventing Dephosphorylation of Iqg1 on Cytokinesis
Innovation Lab Atrium

Comments
Advisor: Katie Shannon
Abstract:
Iqg1 has multiple roles in cytokinesis, including assembly, contraction, and disassembly of the actomyosin ring and coordination of contraction and septation. Since cytokinesis must occur after the completion of mitosis, Iqg1 is cell cycle regulated. I am testing several hypotheses about the regulation of Iqg1: that the binding of Iqg1 to actin is negatively regulated by the cyclin-dependent kinase (CDK) Cdc28 and positively regulated by dephosphorylation by Cdc14. l will test this using Iqg1 mutations that change the amino acid serine to threonine. This will allow phosphorylation but not dephosphorylation.