Location

Innovation Lab Atrium

Start Date

4-2-2025 10:00 AM

End Date

4-2-2025 11:30 AM

Presentation Date

2 April 2025, 10:00am - 11:30am

Biography

Jenna Mueller is a sophomore majoring in Biological Sciences and minoring in Chemistry at Missouri S&T. Along with working in Dr. Shannon’s research lab, Jenna is a pole vaulter on the S&T Track and Field team and is the Vice President of the International Genetically Engineered Machines (iGEM) design team on campus. Jenna aspires to pursue a career in research, focusing on cell and molecular biology or microbiology. Outside of academics and athletics, she enjoys hiking, reading, and watching movies.

Meeting Name

2025 - Miners Solving for Tomorrow Research Conference

Department(s)

Biological Sciences

Second Department

Chemistry

Comments

Advisor: Katie Shannon

Abstract:

Iqg1 has multiple roles in cytokinesis, including assembly, contraction, and disassembly of the actomyosin ring and coordination of contraction and septation. Since cytokinesis must occur after the completion of mitosis, Iqg1 is cell cycle regulated. I am testing several hypotheses about the regulation of Iqg1: that the binding of Iqg1 to actin is negatively regulated by the cyclin-dependent kinase (CDK) Cdc28 and positively regulated by dephosphorylation by Cdc14. l will test this using Iqg1 mutations that change the amino acid serine to threonine. This will allow phosphorylation but not dephosphorylation.

Document Type

Poster

Document Version

Final Version

File Type

text

Language(s)

English

Rights

© 2025 The Authors, All rights reserved

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Apr 2nd, 10:00 AM Apr 2nd, 11:30 AM

The Effects of Preventing Dephosphorylation of Iqg1 on Cytokinesis

Innovation Lab Atrium