Location
Havener Center, St. Pat's Ballroom C
Presentation Date
April 21, 2023, 12:40pm - 1:40pm
Session
Session 2
Description
Despite the large amount of effort going into biological hypo gravity studies, there is little of the opposite. In past studies hyper-gravity has been shown to have a huge impact on both the cellular and organismal level of functionality. In this study hyper-gravity was simulated with centrifugation and inflicted on populations of the model organism Caenorhabditis elegans. The generations that follow were monitored for growth in comparison with populations with the same genetics. Centrifugation of the parental generation varied with intensity. Other factors, including lineage and developmental stage at treatment, were tested. There was no significant divergence in population growth rate or magnitude with variance in stress intensity despite prior evidence pointing to the species having reproductive setbacks with hyper-gravity. Though this data is inconclusive, with the maximum intensity tested being 10,000g, it is clear there would be no setbacks or alteration in data as a consequence of launch into space for study in hypo gravity or as a consequence of vortexing flasks in lab settings.
Meeting Name
32nd Annual Spring Meeting of the NASA-Mo Space Grant Consortium
Department(s)
Biological Sciences
Document Type
Presentation
Document Version
Final Version
File Type
text
Language(s)
English
Rights
© 2023 The Authors, all rights reserved.
The Impact of Hyper-Gravity on C. Elegans Populations in a Laboratory Ecosystem
Havener Center, St. Pat's Ballroom C
Despite the large amount of effort going into biological hypo gravity studies, there is little of the opposite. In past studies hyper-gravity has been shown to have a huge impact on both the cellular and organismal level of functionality. In this study hyper-gravity was simulated with centrifugation and inflicted on populations of the model organism Caenorhabditis elegans. The generations that follow were monitored for growth in comparison with populations with the same genetics. Centrifugation of the parental generation varied with intensity. Other factors, including lineage and developmental stage at treatment, were tested. There was no significant divergence in population growth rate or magnitude with variance in stress intensity despite prior evidence pointing to the species having reproductive setbacks with hyper-gravity. Though this data is inconclusive, with the maximum intensity tested being 10,000g, it is clear there would be no setbacks or alteration in data as a consequence of launch into space for study in hypo gravity or as a consequence of vortexing flasks in lab settings.
