Statistical Methods for Affymetrix Tiling Array Data
Editor(s)
Miliken, George and Johnson, Dallas
Abstract
Tiling arrays are a microarray technology currently being used for a variety of genomic and epigenomic applications, such as the mapping of transcription, DNA methylation, and histone modifications. Tiling arrays provide high-density coverage of a genome, or a genomic region, through the systematic and sequential placement of probes without regard to genome annotation. In this paper we compare the Affymetrix tiling array to the Affymetrix GeneChip® 3’ expression array and propose methods that address statistical and bioinformatic issues that accompany gene expression data that are generated from Affymetrix tiling arrays. Real data from the model organism Arabidopsis thaliana motivate this work and application
Recommended Citation
G. R. Olbricht et al., "Statistical Methods for Affymetrix Tiling Array Data," Proceedings of the Kansas State University Conference on Applied Statistics in Agriculture, 2009, Kansas State University, Jan 2009.
Meeting Name
Applied Statistics in Agriculture: Proceedings of the Kansas State University Conference on Applied Statistics in Agriculture
Department(s)
Mathematics and Statistics
Keywords and Phrases
Microarray; Tiling Array; Differential Expression; ANOVA Model
Document Type
Article - Conference proceedings
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2009 Kansas State University, All rights reserved.
Creative Commons Licensing
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Publication Date
01 Jan 2009