Keywords and Phrases
Drosophila melanogaster; Sleep; Sleep-wake transitions
“Sleep is one of the most preserved and restorative behaviors of animals and is important in human health. Lack of sleep may cause numerous diseases. So the study of sleep rhythms is very essential and complicated. In order to simplify the process of studying sleep, the fruit fly Drosophila melanogaster, is utilized as a model organism for several reasons. Some of the molecular mechanisms that contribute to the circadian clock in the fruit fly were also found to generate similar cycles in mammals. In order to study sleep patterns in the fruit fly, experiments were designed and performed to observe the differences between genotypes and gender of flies. Sleep was also monitored under different environment conditions. Experiments last four days long, with sleep status recorded at each minute. Several variables can be derived from the original data for further statistical analysis. Ultimately it is of interest to characterize the sleep behavior of flies by identifying sleep-related variables based on the four days of sleep. We will investigate if these differ among fly types and genders. So cluster analysis and discriminant analysis has been applied to figure out the key features that would affect sleep cycle of flies. Also, an exponential model of current sleep duration based on past sleep and wake durations is fit to check differences of the parameter estimators between cluster groups”--Abstract, page iii.
Olbricht, Gayla R.
Samaranayake, V. A.
Thimgan, Matthew S.
Mathematics and Statistics
M.S. in Mathematics and Statistics
Missouri University of Science and Technology
viii, 86 pages
© 2014 Luyang Wang, All rights reserved.
Thesis - Open Access
Electronic OCLC #
Wang, Luyang, "Statistical analysis of sleep patterns in Drosophila melanogaster" (2014). Masters Theses. 8069.