"In this thesis, two types of fluidic sensor devices are demonstrated. The first device utilizes a dry film resist (DFR) as the main structural material of fluidic device utilizing the photolithography process. The second one involves a simple, low-cost sensor platform composed of ubiquitous materials such as polymer tubing and metal wires. Both devices are prepared to measure the dissolved oxygen content, as a model target analyte, based on the oxygen quenching reaction of a ruthenium complex fluorophore as the reporting agent. Characterization of sensors is conducted based on the fluorescence lifetime measurement. The first type of sensor is constructed with a novel epoxy-based, optically-transparent DFR (PerMX 3000 series, DuPont). This material is utilized as the main active material for fluidic structure and optical interrogation. The fluorophore is incorporated into a poly( ethylene glycol) (PEG)-based hydro gel material, which is lithographically patterned and embedded inside the PerMX fluidic channel after wafer-bonding process. The device exhibits a good linear response in the biological oxygen saturation range (0 - 21%), demonstrating the promise of PerMX-based fluidic systems as a good device platform for various optofluidic assays. Secondly, an extremely simple assembly of a fluorophore-coated metal wire inserted into a polymeric microbore tube is utilized as the main device structure. We demonstrate that the fluorescence oxygen sensing can be conducted using this cost-effective, I-dimensional device platform. This "lab-in-tube" configuration has a high potential for conducting a streamlined immunoassay procedure with unprecedented convenience for fluidic manipulation"--Abstract, page iv.
Ludlow, Douglas K.
Watkins, Steve Eugene, 1960-
Electrical and Computer Engineering
M.S. in Electrical Engineering
Missouri University of Science and Technology
Journal article titles appearing in thesis/dissertation
- Fluidic sensor devices utilizing dry film resist as main structural material
- Tube-based low-cost optofluidic sensor
x, 60 pages
© 2013 Sijia Gong, All rights reserved.
Thesis - Restricted Access
Library of Congress Subject Headings
Fluidic devices -- Evaluation
Detectors -- Evaluation
Print OCLC #
Electronic OCLC #
Link to Catalog Record
Electronic access to the full-text of this document is restricted to Missouri S&T users. Otherwise, request this publication directly from Missouri S&T Library or contact your local library.http://laurel.lso.missouri.edu/record=b11702007~S5
Gong, Sijia, "Fluidic sensor devices utilizing dry film resist as main structural materials" (2013). Masters Theses. 7587.
Share My Thesis If you are the author of this work and would like to grant permission to make it openly accessible to all, please click the button above.