Masters Theses

Glycoprotein characterization by HPLC-ESI-MS and anticancer drug screening and mechanism study

Junnan Chen

Abstract

"In the first part of this study, we established rapid analytical methods for obtaining approximate information of glycans in a given glycoprotein sample. ... In the second part of this study, we investigated the antitumor activity of 1,2-naphthoquinone-2-thiosemicarbazone (NQTS) and its metal complexes (Cu²⁺, Pd²⁺, and Ni²⁺) against MCF-7 human breast cancer cells and possible mechanisms of their action."--Abstract, page iii.

Department(s)

Chemistry

Degree Name

M.S. in Chemistry

Publisher

University of Missouri--Rolla

Publication Date

Summer 2003

Journal article titles appearing in thesis/dissertation

  • Rapid analysis of glycans in glycoproteins by liquid chromatography and mass spectrometry
  • Anticancer drug screening and mechanism study by capillary electrophoresis and slab gel electrophoresis

Pagination

x, 90 pages

Rights

© 2003 Junnan Chen, All rights reserved.

Document Type

Thesis - Citation

File Type

text

Language

English

Thesis Number

T 8327

Print OCLC #

54907676

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