Development of glass microspheres for radiotherapeutic applications

Author

Thomas A. Wetteroth

Abstract

"Oxide glasses make excellent candidates for radiotherapeutic microspheres used in liver cancer treatment because of their generally high chemical durability and safety of manufacture. From the compositions containing ~5 wt% P₂O₅ studied, magnesium alumino silicate glass microspheres and magnesium alkali silicate glass microspheres with 4 wt% ZrO₂ had acceptably low releases of both elemental phosphorus in deionized water at 50°C, and radioactive ³²P in human blood plasma at 37°C. The relative ranking of glass compositions in the elemental phosphorus leach test shows good agreement with the rankings of compositions in the radioactive ³²P leach test. This correlation can be used to quickly screen future compositions by testing their elemental phosphorus release in deionized water at 50°C prior to the more involved radioactive ³²P leach testing in human blood plasma"--Abstract, page 1.

Advisor(s)

Day, D. E.

Committee Member(s)

Ehrhardt, Gary J.
Anderson, H. U. (Harlan U.)

Department(s)

Materials Science and Engineering

Degree Name

M.S. in Ceramic Engineering

Publisher

University of Missouri--Rolla

Publication Date

Fall 1983

Pagination

vi, 30 pages

Note about bibliography

Includes bibliographical references (pages 17-18).

Rights

© 1983 Thomas A. Wetteroth, All rights reserved.

Document Type

Thesis - Open Access

File Type

text

Language

English

Thesis Number

T 5022

Print OCLC #

10435479

Electronic OCLC #

1044761589

Recommended Citation

Wetteroth, Thomas A., "Development of glass microspheres for radiotherapeutic applications" (1983). Masters Theses. 155.
https://scholarsmine.mst.edu/masters_theses/155