Doctoral Dissertations

Part I. Enantioenrichment of α-hydroxy acids through lipase catalyzed esterification; Part II. Synthesis, purification and characterization of novel molecule, sulfonium (3-hydroxy-3-carboxypropyl)-dimethyl chloride; Part III. Synthesis, purification and characterization of potential cancer chemopreventive compound,2-hydroxy-4-(methyl seleno)-butanioc acid

Shiva Garg

Keywords and Phrases

Novel molecules

Abstract

"This dissertation is divided into three sections that cover three separate but related topics. The first section deals with a preparative scale separation of 2-Hydroxy-4-(methyl thio)-butanoic acid (HMTBA), the hydroxy analog of limiting amino acid Methionine (Met.)...The second section of the dissertation deals with the synthesis of S-methyl HMTBA, an analog of S-methyl methionine (SMM); Vitamin U...The research described in the third section was directed at the synthesis of a selenium analog of HMTBA (Se-HMTBA)--Abstract, page iii.

Advisor(s)

Kapila, Shubhender

Committee Member(s)

Ma, Yinfa
Ercal, Nuran
Nam, Paul Ki-souk
Forciniti, Daniel

Department(s)

Chemistry

Degree Name

Ph. D. in Chemistry

Sponsor(s)

Novus (Firm)

Publisher

University of Missouri--Rolla

Publication Date

Fall 2007

Pagination

xvi, 171 pages

Note about bibliography

Includes bibliographical references (pages 160-170).

Rights

© 2007 Shiva Garg, All rights reserved.

Document Type

Dissertation - Citation

File Type

text

Language

English

Subject Headings

Cancer -- ChemopreventionHydroxy acidsLipaseSelenium compoundsSulfur compounds

Thesis Number

T 9390

Print OCLC #

261216693

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