Lewis acid catalysis in organic synthesis

Author

Ramesh Alleti

Keywords and Phrases

Gadolinium triflate; Michael additons

Abstract

"Gadolinium triflate (Gd(OTf)₃) was found to be a simple and efficient catalyst for the acetylation of alcohols and amines in both conventional organic solvents and as well as in room temperature ionic liquids (TRIL). Acetylation reactions using acetic anhydride as the reagent proceed in excellent yields, in the presence of catalytic amounts (0.01 - 0.5 mol %) of Gd(OTf)₃, at ambient temperature. Acetylations of variety of aliphatic alcohols as well as phenols and amines were proceeded under mild conditions...A novel and efficient catalytic system has been developed for 1,3-dipolar cycloaddition of azides to terminal alkynes using CuCl-RTIL. This catalytical system gives only 1,4-disubstituted 1,2,3-triazoles. Reactions of Alkyl and aryl azides with a variety of terminal alkynes were successfully catalyzed using CuCl-RTIL catalytic system. This catalytic system has the additional characteristics includes simple product isolation, insensitivity to air and moisture, and tolerance to broad range of functional groups"--Abstract, page iii.

Advisor(s)

Reddy, Prakash

Committee Member(s)

Ma, Yinfa
Ercal, Nuran
Sitton, Oliver C., 1951-
Sinn, Ekkehard

Department(s)

Chemistry

Degree Name

Ph. D. in Chemistry

Publisher

University of Missouri--Rolla

Publication Date

Spring 2007

Journal article titles appearing in thesis/dissertation

• Lewis acid catalysis in organic synthesis: ionic liquids as green technology tools
• CuCl-RTIL catalyzed 1,3-dipolar cycloaddition of azides with terminal alkynes

Pagination

x, 123 pages

Note about bibliography

Includes bibliographical references.

Rights

© 2007 Ramesh Alleti, All rights reserved.

Document Type

Dissertation - Citation

File Type

text

Language

English

Subject Headings

CatalysisEnvironmental chemistry -- Industrial applicationsLewis acidsTriazoles

Thesis Number

T 9189

Print OCLC #

191091326

Recommended Citation

Alleti, Ramesh, "Lewis acid catalysis in organic synthesis" (2007). Doctoral Dissertations. 1747.
https://scholarsmine.mst.edu/doctoral_dissertations/1747