Regioselective Fluorination In Synthesis Of Deoxyfluoro Quercitols From D-(-)-quinic Acid

Author

Tzenge Lien Shih
Wen Yu Liao, Missouri University of Science and TechnologyFollow
Wen Chun Yen

Abstract

A facile synthesis of six new deoxyfluoro querciotls from d-(-)-quinic acid is described. The key steps involve the regioselective fluorination as well as highly stereoselective dihydroxylation. These synthetic deoxyfluoro quercitols are considered as potential glycosidase inhibitors.

Recommended Citation

T. L. Shih et al., "Regioselective Fluorination In Synthesis Of Deoxyfluoro Quercitols From D-(-)-quinic Acid," Tetrahedron, vol. 70, no. 51, pp. 9621 - 9627, Elsevier, Dec 2014.

The definitive version is available at https://doi.org/10.1016/j.tet.2014.11.001

Department(s)

Civil, Architectural and Environmental Engineering

Comments

Ministry of Science and Technology, Taiwan, Grant NSC98-2119-M-032-004-MY3

Keywords and Phrases

d-(-)-Quinic acid; Deoxyfluoro quercitols; Fluorination; Glycosidase inhibitors; Regioselective fluorination

International Standard Serial Number (ISSN)

1464-5416; 0040-4020

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2023 Elsevier, All rights reserved.

Publication Date

23 Dec 2014