Nanoscale Sensor Design via in Situ Labeling of Gold Nanoparticles onto Protein Scaffolds
Abstract
A one-step method for synthesis of bioconjugated gold nanoparticles is reported. A non-toxic and biocompatible phosphorus based reducing agent was used for reduction of gold (III) and formation of nanoparticles. Physicochemical properties of protein-A stabilized gold nanoparticls were investigated. Result of immunoassay experiments confirmed the potential of the synthesized anti-protein-A conjugated gold nanoparticles for use as a simple and inexpensive test for quantitative screening of protein-A samples.
Recommended Citation
Z. Afrasiabi Navan et al., "Nanoscale Sensor Design via in Situ Labeling of Gold Nanoparticles onto Protein Scaffolds," Journal of Nanoscience and Nanotechnology, vol. 10, no. 2, pp. 719 - 725, American Scientific Publishers, Feb 2010.
The definitive version is available at https://doi.org/10.1166/jnn.2010.1906
Department(s)
Chemistry
Keywords and Phrases
Gold Nanoparticles; In-situ; Nanoscale sensors; One-step methods; Physicochemical property; Quantitative screening; Antibodies; Gold; Gold compounds; Phosphorus; Sensors; Antibody; Nanoparticles; Protein a.; SensorNanoparticles; gold; metal nanoparticle; protein, article; chemistry; nanotechnology; Gold; Metal Nanoparticles; Nanotechnology; Proteins
International Standard Serial Number (ISSN)
1533-4880
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2010 American Scientific Publishers, All rights reserved.
Publication Date
01 Feb 2010
