Examination of the Enantioselectivity of Wall- Immobilized Cyclodextrin Copolymers in Capillary Gas Chromatography

Author

Yubing Tang
Yiwen Zhou
Daniel W. Armstrong, Missouri University of Science and Technology

Abstract

Approximately 90 chiral compounds were resolved by capillary GC on three different cyclodextrin-based, wall-immobilized capillary columns. Despite similarities in their structure and make-up, these stationary phases often displayed different enantioselectivities. Also their selectivities were different from wall-coated varieties of neat alkyl or alkyl-acyl derivatives of cyclodextrin. It is apparent that the immobilization chemistry affects selectivity as well as stability and efficiency. While the variety of different cyclodextrin-based capillary columns may be disconcerting to many, the practical result is a net increase in the number and types of compounds that can be resolved as well as their expanded usefulness in other capillary techniques. © 1994.

Recommended Citation

Y. Tang et al., "Examination of the Enantioselectivity of Wall- Immobilized Cyclodextrin Copolymers in Capillary Gas Chromatography," Journal of Chromatography A, vol. 666, no. 1 thru 2, pp. 147 - 159, Elsevier, Apr 1994.

The definitive version is available at https://doi.org/10.1016/0021-9673(94)80377-3

Department(s)

Chemistry

Comments

U.S. Department of Energy, Grant DE FG 02 88ER13819

International Standard Serial Number (ISSN)

0021-9673

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2024 Elsevier, All rights reserved.

Publication Date

22 Apr 1994