Capillary Electrophoretic Enantioseparations using Macrocyclic Antibiotics as Chiral Selectors
Abstract
Macrocyclic antibiotics are the newest class of chiral selector used in capillary electrophoresis (CE) enantioseparations. Two basic types of compounds have proven to produce useful enantioseparations. They are the ansa compounds and the glycopeptides. The ansa compounds best resolve basic or cationic racemates while the glycopeptides best resolve acidic or anionic analytes. The structure and use of these chiral selectors are discussed. The factors affecting separation and the separation mechanism are considered as well.
Recommended Citation
D. W. Armstrong and U. B. Nair, "Capillary Electrophoretic Enantioseparations using Macrocyclic Antibiotics as Chiral Selectors," Electrophoresis, vol. 18, no. 12 thru 13, pp. 2331 - 2342, Wiley-VCH Verlag; Wiley, Jan 1997.
The definitive version is available at https://doi.org/10.1002/elps.1150181224
Department(s)
Chemistry
Keywords and Phrases
Avoparcin; Capillary electrophoresis; Enantiomers; Rifamycin B; Rifamyein SV; Ristocetin; Teicoplanin; Vaneomyein
International Standard Serial Number (ISSN)
0173-0835
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2024 Wiley-VCH Verlag; Wiley, All rights reserved.
Publication Date
01 Jan 1997
PubMed ID
9456048
