Abstract
The use of mixtures of sulfated β-cyclodextrins and native α-cyclodextrin as chiral additives in capillary electrophoresis was evaluated for the chiral resolution of neutral, cyclic and bicyclic monoterpenes, including α-pinene, (β-pinene, camphene and limonene. Binding properties of sulfated β-cyclodextrins towards these monoterpenes were studied. It was found that there was no enantioresolution of these terpenoids over the concentration range studied. However, the addition of α-cyclodextrin to the running electrolyte in addition to 6.5 mM sulfated β-cyclodextrins, imparted differences in the mobilities of the terpenoid enantiomers and resulted in remarkable enantiomeric separations of α-pinene (R(s)=25), β-pinene (R(s)=12), camphene (R(s)=12) and limonene (R(s)=4). The role of both α-cyclodextrin and sulfated β-cyclodextrins in these separations is discussed.
Recommended Citation
K. H. Gahm et al., "Chiral Separation of Monoterpenes using Mixtures of Sulfated Β-Cyclodextrins and Α-Cyclodextrin as Chiral Additives in the Reversed-Polarity Capillary Electrophoresis Mode," Journal of Chromatography A, vol. 759, no. 1 thru 2, pp. 149 - 155, Elsevier, Jan 1997.
The definitive version is available at https://doi.org/10.1016/S0021-9673(96)00747-9
Department(s)
Chemistry
Keywords and Phrases
Buffer composition; Cyclodextrin additives; Cyclodextrins; Enantiomer separation; Monoterpenes; Pinenes; Terpenes
International Standard Serial Number (ISSN)
0021-9673
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2024 Elsevier, All rights reserved.
Publication Date
24 Jan 1997
