Brain Composition: Age-Related Changes
Abstract
Aging and age-related disease are marked by oxidative modification and consequent reduced function for protein, lipids, sugars, and nucleic acids. Alterations in redox active metals play critical roles in catalyzing these oxidative modifications. This brief review presents an overview of the major features and chemistry of oxidative modification and metal homeostasis.
Recommended Citation
V. P. Reddy et al., "Brain Composition: Age-Related Changes," The Curated Reference Collection in Neuroscience and Biobehavioral Psychology, pp. 313 - 316, Elsevier, Jan 2016.
The definitive version is available at https://doi.org/10.1016/B978-0-12-809324-5.02591-8
Department(s)
Chemistry
Keywords and Phrases
Alzheimer disease; Copper; Glycation; Iron; Lipid peroxidation; Nitration; Nucleic acid oxidation; Oxidative stress
International Standard Book Number (ISBN)
978-012809324-5
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2024 Elsevier, All rights reserved.
Publication Date
01 Jan 2016
