Abstract
Polymeric materials based upon 2-hydroxyethyl methacrylate (HEMA) have been extensively used, especially in biomedical applications. Several reports have appeared in the literature during the past 20 years regarding the behavior of these materials upon exposure to body fluids. The results of these studies have ranged from good biocompatibility to calcification. The presence of methacrylic acid (MAA), in HEMA-based copolymers gives rise to a swelling transition at pH 7. The present study relates the swollen volume of HEMA/MAA gels to the concentrations of calcium salts at a pH where the MAA is ionized, as would occur for implanted gels. This swollen volume relationship is critical to implants which rely on dimensional integrity.
Recommended Citation
M. R. Van De Mark et al., "INTERACTION OF CALCIUM WITH HEMA/MAA COPOLYMERS.," Journal of Polymer Science, Part C: Polymer Letters, vol. 25, no. 8, pp. 327 - 330, Wiley, Jan 1987.
The definitive version is available at https://doi.org/10.1002/pol.1987.140250804
Department(s)
Chemistry
Publication Status
Full Access
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2023 Wiley, All rights reserved.
Publication Date
01 Jan 1987
