Interaction Of A Model Epidermal Lipid With A Vegetable Oil Adduct

Abstract

A study of the interaction between a model epidermal lipid and 2(alkoyloxy)-1-[(alkoyloxy)methyl]-ethyl-7-(4 hepty1-5, 6-dicarboxyl-2-cyclohexene-1-yl)heptanoate, (G2) was made by use of small angle X-ray diffraction. The small angle X-ray diffraction pattern of the epidermal lipid model was first compared to the X-ray pattern obtained from human stratum corneum. Increase in the water content of the model epidermal lipid from 32% to 35% caused a shift in the broad diffraction peak from 50–80Å to 50–70Å. No additional shift was found at further addition of water. The addition of G2 to the 32% water model also caused a shift toward smaller interlayer spacing. The effect of G2 was most dramatic for the model epidermal lipid at the lowest water content. © 1987, Taylor & Francis Group, LLC. All rights reserved.

Department(s)

Chemistry

International Standard Serial Number (ISSN)

1532-2351; 0193-2691

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2023 Taylor and Francis Group; Taylor and Francis, All rights reserved.

Publication Date

01 Jun 1987

Share

 
COinS