Liquid Chromatographic Separation Of Anomeric Forms Of Saccharides With Cyclodextrin Bonded Phases

Author

Daniel W. Armstrong, Missouri University of Science and Technology
Heng L. Jin

Abstract

A brief review of sugar stereochemistry is given. The separation of 84 different pairs of anomers was accomplished on both α‐ and β‐cyclodextrin columns. Five different mobile phases were evaluated. The separation of anomers temperature, flow rate, and so on. The separation of anomers that mutarotate is somewhat more difficult than those that do not. Prior knowledge as to the rate of mutaroation is useful so that the chromatographic conditions can be arranged to minimize any deleterious effects on the separation. Copyright © 1989 Alan R. Liss, Inc.

Recommended Citation

D. W. Armstrong and H. L. Jin, "Liquid Chromatographic Separation Of Anomeric Forms Of Saccharides With Cyclodextrin Bonded Phases," Chirality, vol. 1, no. 1, pp. 27 - 37, Wiley, Jan 1989.

The definitive version is available at https://doi.org/10.1002/chir.530010108

Department(s)

Chemistry

Comments

National Institute of General Medical Sciences, Grant R01GM036292

Keywords and Phrases

carbohydrates; hemiacetal; isomeric; mutarotation; optimization; selectvity; separation; sugars; temperature effects

International Standard Serial Number (ISSN)

1520-636X; 0899-0042

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2023 Wiley, All rights reserved.

Publication Date

01 Jan 1989

PubMed ID

2642034