2,6-Di-O-pentyl-3-O-trifluoroacetyl Cyclodextrin Liquid Stationary Phases For Capillary Gas Chromatographic Separation Of Enantiomers
Abstract
A series of liquid cyclodextrin derivatives, 2,6-di-O-pentyl-3-O-trifluoroacetyl α-, β- and γ-cyclodextrins (DP-TFA α-, β- and γ-CD), have been used as highly selective chiral stationary phases for capillary gas chromatography. More than 150 pairs of enantiomers were resolved; 120 on DP-TFA-γ-CD, which is the first reported γ-cyclodextrin stationary phase that is more widely useful than the β-cyclodextrin analogue. The enantiomers resolved include chiral alcohols, diols, polyols, amines, amino alcohols, halohydrocarbons, lactones, α-halocarboxylic acid esters, carbohydrates, epoxides, nicotine compounds, pyrans, furans and so on. Identical α values were observed for diol, amine and γ-halocarboxylic acid ester homologues, respectively. The relationship between the unusual selectivity behavior and separation mechanism is discussed. © 1990.
Recommended Citation
W. Y. Li et al., "2,6-Di-O-pentyl-3-O-trifluoroacetyl Cyclodextrin Liquid Stationary Phases For Capillary Gas Chromatographic Separation Of Enantiomers," Journal of Chromatography A, vol. 509, no. 2, pp. 303 - 324, Elsevier, Jan 1990.
The definitive version is available at https://doi.org/10.1016/S0021-9673(01)93089-4
Department(s)
Chemistry
International Standard Serial Number (ISSN)
0021-9673
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2023 Elsevier, All rights reserved.
Publication Date
01 Jan 1990
