Liquid Crystals As A Potential Ointment Vehicle
Abstract
A lecithin‐water lyotropic liquid crystal was used as an ointment vehicle for a hydrocortisone formulation. The hydrocortisone was soluble in the liquid crystalline phase up to 5% by weight. The diffusion coefficient determined for the hydrocortisone in the liquid crystalline phase was 5.5 x 10−9 cm·s−1, which is four magnitudes higher than the corresponding value for skin. Copyright © 1984 Wiley‐Liss, Inc., A Wiley Company
Recommended Citation
S. Wahlgren et al., "Liquid Crystals As A Potential Ointment Vehicle," Journal of Pharmaceutical Sciences, vol. 73, no. 10, pp. 1484 - 1486, Elsevier, Jan 1984.
The definitive version is available at https://doi.org/10.1002/jps.2600731042
Department(s)
Chemistry
Keywords and Phrases
Hydrocortisone—lecithin‐water liquid crystals as potential ointment vehicle; Lecithin—liquid crystals as potential ointment vehicle; Ointments—vehicles, liquid crystals, lecithin‐water
International Standard Serial Number (ISSN)
1520-6017; 0022-3549
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2023 Elsevier, All rights reserved.
Publication Date
01 Jan 1984
PubMed ID
6502503
