The Rate Of Adhesion Of Melanoma Cells Onto Nonionic Polymer Surfaces
The rates of adhesion of melanoma cells (carcinogenic) onto nonionic polymer surfaces were studied by using radioactively labeled cells and measuring the fraction of cells which adhered to the surface in a given time. Glow discharge (plasma) polymerization of 1,1,3,3‐tetramethyldisiloxane and of nitrogen‐acetylene‐water (mole ratio 0.4:1.0:0.2) was used to modify the surface energy of the substrate. The cell adhesion rate was found to be given by Y = 1 − exp [−k0(γs − γ0)t], where Y is the fraction of cells adhered, − k0 is a characteristic rate constant, γs is the total surface energy of the substrate, γ0 is the threshold surface energy of cell adhesion, and t is time. Copyright © 1978 John Wiley & Sons, Inc.
H. Yasuda et al., "The Rate Of Adhesion Of Melanoma Cells Onto Nonionic Polymer Surfaces," Journal of Biomedical Materials Research, vol. 12, no. 5, pp. 701 - 706, Wiley, Jan 1978.
The definitive version is available at https://doi.org/10.1002/jbm.820120510
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01 Jan 1978