The Rate Of Adhesion Of Melanoma Cells Onto Nonionic Polymer Surfaces
Abstract
The rates of adhesion of melanoma cells (carcinogenic) onto nonionic polymer surfaces were studied by using radioactively labeled cells and measuring the fraction of cells which adhered to the surface in a given time. Glow discharge (plasma) polymerization of 1,1,3,3‐tetramethyldisiloxane and of nitrogen‐acetylene‐water (mole ratio 0.4:1.0:0.2) was used to modify the surface energy of the substrate. The cell adhesion rate was found to be given by Y = 1 − exp [−k0(γs − γ0)t], where Y is the fraction of cells adhered, − k0 is a characteristic rate constant, γs is the total surface energy of the substrate, γ0 is the threshold surface energy of cell adhesion, and t is time. Copyright © 1978 John Wiley & Sons, Inc.
Recommended Citation
H. Yasuda et al., "The Rate Of Adhesion Of Melanoma Cells Onto Nonionic Polymer Surfaces," Journal of Biomedical Materials Research, vol. 12, no. 5, pp. 701 - 706, Wiley, Jan 1978.
The definitive version is available at https://doi.org/10.1002/jbm.820120510
Department(s)
Chemistry
International Standard Serial Number (ISSN)
1097-4636; 0021-9304
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2023 Wiley, All rights reserved.
Publication Date
01 Jan 1978
PubMed ID
359560
