Intracerebral Hemorrhage: External Validation and Extension of a Model for Prediction of 30‐day Survival

Author

Stanley Tuhrim
James M. Dambrosia
Thomas R. Price
Jay P. Mohr
Philip A. Wolf
Daniel B. Hier, Missouri University of Science and TechnologyFollow
Carlos S. Kase

Abstract

We Report Validation of a Previously Reported Logistic Regression Model for Predicting 30‐day Survival after Supratentorial Intracerebral Hemorrhage using Independent, Propectively Collected Data. the Original Model, using Initial Glasgow Coma Scale Score, Hemorrhage Size, and Pulse Pressure, Accounted for Mortality or Survival at 30 Days in 92% of Patients in the Pilot Stroke Data Bank with a Sensitivity of 0.84 and a Specificity of 0.96. for External Validation, the Model Was Used to Predict 30‐day Status for Each Patient in the Main Phase Stroke Data Bank for Whom Complete Risk Factor Information Was Available. overall, 90% of Patients' Outcomes Were Correctly Predicted with a Sensitivity of 0.85 and a Specificity of 0.92. Two Factors Not Collected in the Pilot Stroke Data Bank, Hyperglycemia and Intraventricular Hemorrhage Extension, Were Assessed to Determine If They Provided Additional Predictive Information on 30‐day Mortality. Intraventricular Hemorrhage Extension Contributed Significant Predictive Information in a Logistic Regression, Whereas Hyperglycemia Did Not. the Resulting Four‐factor Model with an Interaction Term (Intraventricular Hemorrhage Extension and Glasgow Coma Scale Score) Correctly Classified the Survival Status of 94% of Patients at 30 Days. a More General Outcome, Death or Failure to Achieve a "Good" Activities O Daily Living Score by One Year, Was Analyzed with Respect to the Same Four Factors. the Resulting Model Correctly Classified 95% of the Patients in the Cohort. Copyright © 1991 American Neurological Association

Recommended Citation

S. Tuhrim et al., "Intracerebral Hemorrhage: External Validation and Extension of a Model for Prediction of 30‐day Survival," Annals of Neurology, vol. 29, no. 6, pp. 658 - 663, Wiley, Jan 1991.

The definitive version is available at https://doi.org/10.1002/ana.410290614

Department(s)

Chemistry

Comments

National Institute of Neurological Disorders and Stroke, Grant N01NS022302

International Standard Serial Number (ISSN)

1531-8249; 0364-5134

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2023 Wiley, All rights reserved.

Publication Date

01 Jan 1991

PubMed ID

1842899