Impaired Insight in Alzheimer's Disease
We Studied Insight into Illness in 41 Patients with Probable Alzheimer's Disease. an Impaired Insight Score Was Developed by Measuring Discrepancies between Patient Report and Caregiver Report on Standard Instruments of Activities of Daily Living. Insight Was More Impaired in Subjects with Greater Dementia Severity and Subjects with Paranoid Delusions. in a Multivariate Analysis, the Best Neuropsychological Predictors of Impaired Insight Were the Continuous Performance Test and the Visual Reproduction Test. We Speculate that the Impaired Insight of Alzheimer's Disease Has Two Components: Confabulation Reflecting Prefrontal Dysfunction and Anosognosia Reflecting Right-Hemisphere Dysfunction. (J Geriatr Psychiatry Neurol 1991;4:189-193). © 1991, Sage Publications. All Rights Reserved.
C. A. Mangone et al., "Impaired Insight in Alzheimer's Disease," Journal of Geriatric Psychiatry and Neurology, vol. 4, no. 4, pp. 189 - 193, SAGE Publications, Jan 1991.
The definitive version is available at https://doi.org/10.1177/089198879100400402
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01 Jan 1991
National Institute on Aging, Grant K08AG000350