Impaired Insight in Alzheimer's Disease

Abstract

We Studied Insight into Illness in 41 Patients with Probable Alzheimer's Disease. an Impaired Insight Score Was Developed by Measuring Discrepancies between Patient Report and Caregiver Report on Standard Instruments of Activities of Daily Living. Insight Was More Impaired in Subjects with Greater Dementia Severity and Subjects with Paranoid Delusions. in a Multivariate Analysis, the Best Neuropsychological Predictors of Impaired Insight Were the Continuous Performance Test and the Visual Reproduction Test. We Speculate that the Impaired Insight of Alzheimer's Disease Has Two Components: Confabulation Reflecting Prefrontal Dysfunction and Anosognosia Reflecting Right-Hemisphere Dysfunction. (J Geriatr Psychiatry Neurol 1991;4:189-193). © 1991, Sage Publications. All Rights Reserved.

Department(s)

Chemistry

Comments

National Institute on Aging, Grant K08AG000350

International Standard Serial Number (ISSN)

1552-5708; 0891-9887

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2023 SAGE Publications, All rights reserved.

Publication Date

01 Jan 1991

PubMed ID

1789906

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