Designed 3D DNA Crystals
The simplest practical route to producing precisely designed 3D macroscopic objects is to form a crystalline arrangement by self-assembly, because such a periodic array has only conceptually simple requirements: a motif that has a robust 3D structure, dominant affinity interactions between parts of the motif when it self-associates, and predictable structures for these affinity interactions. Fulfilling these three criteria to produce a 3D periodic system is not easy, but should readily be achieved with well-structured branched DNA motifs tailed by sticky ends (Zheng et al., Nature 461:74-77, 2009). Herein, a brief introduction to designed 3D DNA crystals from tensegrity triangle is presented.
N. C. Seeman et al., "Designed 3D DNA Crystals," Methods in Molecular Biology, vol. 1500, pp. 3-10, Humana Press Inc., Jan 2017.
The definitive version is available at https://doi.org/10.1007/978-1-4939-6454-3_1
Keywords and Phrases
DNA crystal; Self-assembly
International Standard Book Number (ISBN)
International Standard Serial Number (ISSN)
Book - Chapter
© 2017 Springer Science+Business Media New York, All rights reserved.
01 Jan 2017