Metal-Catalyzed and Metal-Free Intermolecular Amination of Light Alkanes and Benzenes

Author

Pericles Stavropoulos, Missouri University of Science and TechnologyFollow

Abstract

Light alkanes (C₁-C₁₀) and simple aromatics are derived from desirable crude energy feedstock but present challenging cases for C–H functionalization purposes. This article reviews efforts to mediate C–N bond construction from these abundant sources to generate commodity chemicals of high industrial value. The nitrogen-group donors considered are largely limited to metal-bound or diffusively free nitrenes, nitrenoids, and amides/imides engaged in catalytic or stoichiometric intermolecular reactions. Both synthetic protocols and mechanistic studies are discussed to illustrate the current status of a rapidly developing field that is still in need of significant improvements to effect reactive and selective processes.

Recommended Citation

P. Stavropoulos, "Metal-Catalyzed and Metal-Free Intermolecular Amination of Light Alkanes and Benzenes," Comments on Inorganic Chemistry, vol. 37, no. 1, pp. 1 - 57, Taylor & Francis Inc., Jan 2017.

The definitive version is available at https://doi.org/10.1080/02603594.2016.1183487

Department(s)

Chemistry

International Standard Serial Number (ISSN)

0260-3594

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2017 Taylor & Francis Inc., All rights reserved.

Publication Date

01 Jan 2017