Control of DNA Origami Inter-Tile Connection with Vertical Linkers
This communication describes a new method that enables high yield assembly along both of the two-dimensional edges of DNA origami tiles by controlling the Mg2+ concentration; high Mg2+ concentrations promote linkage connections between the vertical edges of the tiles. As a demonstration, DNA origami dimers assembled from two rectangular origami along the vertical edges are used as scaffolds for the double sided assembly of gold nanoparticles with different inter-particle spacings.
R. Wang et al., "Control of DNA Origami Inter-Tile Connection with Vertical Linkers," Chemical Communications, vol. 52, no. 8, pp. 1610-1613, Royal Society of Chemistry, Nov 2016.
The definitive version is available at https://doi.org/10.1039/c5cc08185h
Keywords and Phrases
DNA; Gold; Magnesium; Metal Nanoparticles; Microscopy, Atomic Force
International Standard Serial Number (ISSN)
Article - Journal
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