Control of DNA Origami Inter-Tile Connection with Vertical Linkers

Author

Risheng Wang, Missouri University of Science and TechnologyFollow
Kent Gorday
Colin Nuckolls
Shalom J. Wind

Abstract

This communication describes a new method that enables high yield assembly along both of the two-dimensional edges of DNA origami tiles by controlling the Mg²⁺ concentration; high Mg²⁺ concentrations promote linkage connections between the vertical edges of the tiles. As a demonstration, DNA origami dimers assembled from two rectangular origami along the vertical edges are used as scaffolds for the double sided assembly of gold nanoparticles with different inter-particle spacings.

Recommended Citation

R. Wang et al., "Control of DNA Origami Inter-Tile Connection with Vertical Linkers," Chemical Communications, vol. 52, no. 8, pp. 1610 - 1613, Royal Society of Chemistry, Nov 2016.

The definitive version is available at https://doi.org/10.1039/c5cc08185h

Department(s)

Chemistry

Keywords and Phrases

DNA; Gold; Magnesium; Metal Nanoparticles; Microscopy, Atomic Force

International Standard Serial Number (ISSN)

1359-7345

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2016 Royal Society of Chemistry, All rights reserved.

Publication Date

01 Nov 2016

PubMed ID

26662034