Recent trends in Friedel-Crafts and related electrophilic reactions, using a variety of Lewis and Brønsted acid catalysts, are comprehensively reviewed. The Friedel-Crafts reactions include alkylations, acylations, hydroxylations, nitrations, halogenations, aminations, sulfuration, sulfinylation, and sulfonylation of aromatic and olefinic hydrocarbons. The nature and types of acid catalysts are discussed, including superelectrophilic activation. Representative stereoselective Friedel-Crafts alkylations are also described.
P. Reddy and G. K. Prakash, "Friedel-Crafts Reactions," Kirk-Othmer Encyclopedia of Chemical Technology, John Wiley & Sons, Apr 2013.
The definitive version is available at https://doi.org/10.1002/0471238961.0618090515120108.a01.pub2
Keywords and Phrases
Freidel-Crafts Reactions; Lewis and Bronsted Acid Catalysts; Electrophilic Reactions
Book - Chapter
© 2013 John Wiley & Sons, All rights reserved.
19 Apr 2013