Prototyping Nanorod Control: A DNA Double Helix Sheathed within a DNA Six-Helix Bundle

Abstract

The control of the structure of matter is a key goal of nanoscience. DNA is an exciting molecule for control because it forms programmable intermolecular interactions. Stiff DNA structures, such as the double crossover motif, the tensegrity triangle, and the six-helix bundle (6HB) have been used to produce periodic arrays of DNA components. the 6HB motif consists of six DNA double helices flanking an inner cavity whose diameter is similar to that of a double helix. This motif appears to be an excellent candidate to sheathe and control nanorods by inserting them into the cavity, and then to control the placement and orientation of the rod by controlling the DNA sheath. Here, we prototype this kind of control by using a seventh DNA double helix as the nanorod and fixing it inside the 6HB motif.

Department(s)

Chemistry

Keywords and Phrases

DNA; Hydroxyl Radical; Nanotube; Atomic Force Microscopy; Chemistry; Metabolism; Molecular Genetics; Nucleotide Sequence; Ultrastructure; Molecular Sequence Data

International Standard Serial Number (ISSN)

1074-5521

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2009 Elsevier, All rights reserved.

Publication Date

01 Aug 2009

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