Blunt-Ended DNA Stacking Interactions in a 3-Helix Motif

Author

Risheng Wang, Missouri University of Science and TechnologyFollow
Akinori Kuzuya
Wenyan Liu, Missouri University of Science and TechnologyFollow
Nadrian C. Seeman

Abstract

We demonstrate that intermolecular stacking is capable of forming one-dimensional arrays of a blunt-ended 3-helix DNA motif. the array can be visualized in the atomic force microscopy through conjugated streptavidin nanoparticles. We estimate the strength of the triple stacking interaction to be -8.6 kcal mol^-1.

Recommended Citation

R. Wang et al., "Blunt-Ended DNA Stacking Interactions in a 3-Helix Motif," Chemical Communications, vol. 46, no. 27, pp. 4905 - 4907, Royal Society of Chemistry, Jun 2010.

The definitive version is available at https://doi.org/10.1039/c0cc01167c

Department(s)

Chemistry

Keywords and Phrases

DNA; Nanoparticle; Streptavidin; Atomic Force Microscopy; DNA Determination; DNA Structure; Molecular Interaction; Chemistry; Conformation; Nucleotide Sequence; Thermodynamics; Base Sequence; Nucleic Acid Conformation

International Standard Serial Number (ISSN)

1359-7345

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2010 Royal Society of Chemistry, All rights reserved.

Publication Date

01 Jun 2010

PubMed ID

20532374