Immobilization of Pd Catalysts on Mesoporous Silica for Amine-, and Copper-free Sonogashira Coupling Reactions

Author

Chariklia Sotiriou-Leventis, Missouri University of Science and TechnologyFollow
Xiaojiang Wang
Sudhir Mulik
Arumugam Thangavel
Nicholas Leventis, Missouri University of Science and TechnologyFollow

Abstract

Immobilization of catalysts on solid supports is a promising approach to combine the advantages of heterogeneous and homogeneous catalysts. Pd(PPh3)2Cl2, known as an extremely active homogeneous catalyst for the Sonogashira coupling reaction, has been immobilized on high-surface-area MCF (mesocellular foams)-type mesoporous silica powder modified with 3-aminopropyltriethoxysilane and subsequently with diphenylphosphine. The functionalized MCF-type silica and supported catalysts have been characterized by x-ray photoelectron spectroscopy (XPS), fourier transform infrared spectroscopy (FTIR), elemental analysis, nitrogen sorption porosimetry, and scanning electron microscopy (SEM). Such supported Pd catalysts have proven to be useful recyclable reagents for copper- and amine-free Sonogashira coupling reactions of haloaromatic compounds with terminal alkynes.

Recommended Citation

C. Sotiriou-Leventis et al., "Immobilization of Pd Catalysts on Mesoporous Silica for Amine-, and Copper-free Sonogashira Coupling Reactions," Synthetic Communications, Taylor & Francis, Jan 2008.

The definitive version is available at https://doi.org/10.1080/00397910802138546

Department(s)

Chemistry

International Standard Serial Number (ISSN)

0039-7911

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2008 Taylor & Francis, All rights reserved.

Publication Date

01 Jan 2008